IntegriCulture to Accelerate Cultivated Meat Commercialization Capability with Proprietary Cell Agriculture System, Supported by Japanese Authority Grant

- $2 Million fund will support to achieve sustainable food by enabling more varieties of cultivated meat at lower cost by automation of animal cell culture -

Tokyo, Japan, July 25, 2022 — IntegriCulture Inc. (hereafter IntegriCulture), a Japanese cellular agriculture startup pioneering revolutionary advancements in cellular agriculture and aims for a sustainable world, today announced to receive a grant from NEDO¹ (New Energy and Industrial Technology Development Organization), to accelerate the development of technologies for the practical application and mass production of cultivated meat from a wider range of animal and cell types, and to reduce the production costs of various types of meat, with the aim of achieving to integrate the advanced technology into mass production technology and provide it to companies that do not have cell culture technology.

IntegriCulture aims to popularize cultivated meat through its proprietary cell culture technology, the CulNet™ system. The system is a device that artificially creates an environment similar to that inside an animal's body to grow cells. The cells of animals such as cows and chickens can be doubled in 1.5 to 2 days using the CulNet system.

The high cost of growth medium components is no longer necessary because they can be generated within the CulNet system by simulating the in-vivo natural organ communication processes. The system allows us to internalize the production of growth medium by only basal medium and selected cells². This proprietary system will directory contribute to reduce the production cost of cultivated meat and the needs of growth factors as additives. IntegriCulture plans to expand the cell culture protocols for different type of meat; duck liver, chicken, beef, port, shrimp or other commonly consumed meats. IntegriCulture will use the NEDO grant to accelerate the development of cellular agriculture technologies for commercial applications and mass production.

Demonstrations in more animal species are key to the full-scale spread of cultivated meat.

Yuki Hanyu, CEO at IntegriCulture said: “A glass vat that does whole tissue culture of any organs of any species, using basal medium only – it sounds like a sci-fi dream to some - that is an exact description of CulNet system we’re developing.”

In December 2022, IntegriCulture plans to achieve the first production milestone of 8 kilograms of cultured meat per month at a cost of approximately US$ 300 per 100 grams. We aim for 20 tons production per month at nearly US$1 per 100 grams in 2028 by scaling the facility. While the current cultivated meat is in the form of paste, we plan to produce a steak (structured tissue) meat in 2026 as our technology development goal.

Notes to editors:

1 NEDO: a Japanese national research and development agency that creates innovation by promoting technological development necessary for realization of a sustainable society.

2 Cultivated meat production using only basic culture medium: Further validation tests are currently underway.

About IntegriCulture Inc.

IntegriCulture, we, aim to use our proprietary cost-competitive cell culture technology "CulNet™ system" as a new platform in the biotechnology field, and to use it in various fields such as foods and leather made up of animal cells.
The system in principle cultures any cells and produce anything produced by living things. It is astounding versatility makes it ideal for a general platform for clients wanting to produce food, cosmetics, supplements, functional ingredients, pharmaceuticals, and any other biological and agricultural products.
Also, it is not necessary to use fetal bovine serum and growth factors, which are the main causes of high cost of conventional cell culture, and the cost of cell culture can be significantly reduced.
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